Custom Bioinformatics Services and Contract Support for Complex Projects

We cover more ground - from RNA-seq to metagenomics, epigenomics, machine learning, and more.

Our Lead Bioinformaticians and engineering team work across major omics technologies, supporting model and non-model organisms, bulk and single-cell workflows, and both clinical and environmental datasets. Our offerings include:

1. Whole-genome and exome analysis - genome assembly, variant calling, and hybrid integration

2. RNA-seq analysis - bulk RNA-seq, scRNA-seq, scATAC-seq, and Multiome - see our expert’s insights on analyzing scRNA-seq and Multiome data

3. Epigenomics - ATAC-seq, ChIP-seq, CUT&Tag, CUT&RUN, and DNA methylation (WGBS, RRBS, EPIC array, scBS-seq):

‣ Our senior bioinformatician’s reflections on real-world epigenomic analysis

‣ Our Lead Bioinformatician’s take on troubleshooting peak-based assays

‣ Our expert’s overview of common DNA methylation analysis pitfalls

4. Spatial transcriptomics - Visium, Xenium, CosMx - see our expert’s guide to solving spatial transcriptomics challenges

5. Long-read data analysis - PacBio, Oxford Nanopore, Iso-Seq, and hybrid pipelines:

‣ Our Lead Bioinformatician’s comparison of sequencing platforms

‣ Our senior team’s thoughts on long-read assembly, isoforms, and methylation

6. Multi-omics integration - transcriptomics, ATAC-seq, methylation, proteomics, metabolomics - see our expert’s guidance on robust multi-omics integration

7. Association studies - GWAS, EWAS, TWAS, PWAS:

‣ Our expert’s quick-start guide to GWAS

‣ Our senior bioinformatician’s advice on avoiding five common GWAS mistakes

‣ Our Lead Bioinformatician’s perspective on post-GWAS approaches like TWAS and EWAS

8. Machine learning - predictive modeling, biomarker discovery, large language models - see our expert’s rundown of 10 real-world AI applications in biology

9. AlphaFold and structural modeling - protein structure prediction using AlphaFold 2 & 4:

‣ Our senior bioinformatician’s explanation of why AlphaFold 2 is so powerful

‣ Our expert’s take on how AlphaFold 4 is being used in real research

10. Microbiome and metagenomics - 16S and shotgun workflows - see our expert’s insights on functional microbiome profiling

11. Proteomics and mass spectrometry - DIA/TMT pipelines, robust quantification, batch correction - see our bioinformatician’s experience solving real proteomics analysis challenges

12. Custom pipelines and troubleshooting - single-cell quirks, over-tagmented libraries, and non-standard designs

Want more real-world examples across these domains? Browse our full expert-written blog series.